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San Francisco 49ers wide receiver Brandon Aiyuk celebrates as we look at our anytime touchdown scorer predictions for Thursday Night Football
San Francisco 49ers wide receiver Brandon Aiyuk celebrates. Photo Credit: Sergio Estrada-Imagn Images.

First place in the NFC West is on the line tonight as the Seattle Seahawks host the San Francisco 49ers as underdogs by the Thursday Night Football odds.

Add to the thrill of Thursday Night Football and your 49ers vs. Seahawks prediction with the help of our anytime touchdown scorer predictions.

We need to dig ourselves out of a hole after a horrible Week 5 with our picks. But there's plenty of value across our NFL prop betting sites as we add to Phil Wood's 49ers vs. Seahawks TNF prop bets.

We dive further into the scoring market with our first touchdown scorer predictions focusing on two tight ends.

Anytime touchdown scorer predictions for Thursday Night Football: 49ers vs. Seahawks

49ers anytime touchdown scorer pick: Brandon Aiyuk, WR ⭐⭐⭐⭐

Best odds: | Implied probability: 39.22%

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After a rough go in Week 5, which ended with a couple of near misses during Monday Night Football, we're going to start Week 6 with some more conservative plays.

The Seahawks have been strong at defending opposing wide receivers, limiting the position to 581 yards on 53 receptions (80 targets) through five weeks. However, they've given up five touchdowns wideouts.

Aiyuk notably hasn't scored this season following a training camp holdout, but he's been targeted at least five times in every game. He set season highs last week with 12 targets, eight receptions, and 147 yards in a loss to the Arizona Cardinals. He also played 92% of the snaps.

FanDuel is the place to make this Thursday night prop bet with a winning $10 wager returning a profit of $15.50. The same bet at Caesars would fetch just a $12.70 profit.

We're targeting the touchdown odds for another 49ers receiver in our Deebo Samuel TNF player prop bets. We also expect a strong day for San Francisco's quarterback as part of our Brock Purdy TNF player prop bets.

Seahawks anytime touchdown scorer pick: Zach Charbonnet ⭐⭐⭐

Best odds: +340 via FanDuel | Implied probability: 22.73%

Charbonnet has been maintaining a prominent role in Seattle's offense even after starter Kenneth Walker III returned from a two-game injury absence in Week 4. The second-year, second-round pick played at least 36% of the snaps in each of his team's last two contests, totaling 12 touches for 84 yards.

Though he remains at four total touchdowns on the season (with none in the last two weeks), I like this spot for the versatile back.

San Francisco has been limiting running backs to 4.17 yards per carry, but its 7.28 yards per target allowed is much friendlier for this pick. Charbonnet has kept his presence via Seattle's passing game, logging 18 receptions to Walker's 13 this season.

The Seahawks should continue passing often as 3.5-point home underdogs by the NFL Week 6 odds.

We're also targeting another running back tonight as part of our 49ers vs. Seahawks TNF parlay.

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