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On their way to the season’s conclusion, the big clubs around Europe’s top leagues will be involved in another weekend of exciting action. Our soccer best bets focus on what's going on in La Liga, Serie A, and Bundesliga this weekend.

By far, the most glamorous encounter this weekend is the Milan Derby between Inter and AC Milan on Sunday, but FC Barcelona, Bayern Munich, and Borussia Dortmund will also be playing high-profile matches in their respective leagues.

Here are our best bets from Serie A, La Liga, and Bundesliga ahead of the European soccer weekend (odds via  and ; pick confidence based on a 1-to-5-star scale).

Check out all of our top soccer picks and our Champions League odds.

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Soccer best matches and odds this week

(odds via FanDuel)

  • Serie A: Inter (-105) vs. AC Milan (+280), Sunday, 2:45 p.m. ET
  • Bundesliga: Dortmund (-165) vs. Freiburg (+400), Saturday, 9:30 a.m. ET
  • Bundesliga: Wolfsburg (+400) vs. Bayern Munich (-185), Sunday, 11:30 a.m. ET
  • La Liga: Mallorca (+490) vs. Real Madrid (-175), Sunday, 8 a.m. ET
  • La Liga: Barcelona (-340) vs. Sevilla (+750), Sunday, 3 p.m. ET

Soccer best bets: February 2-6

  • Total: Eintracht Frankfurt-Hertha Berlin Over 3.5 (+144 via FanDuel) ⭐⭐⭐
  • Spread: Napoli -1 vs. Spezia (+100 vs BetMGM) ⭐⭐⭐⭐
  • Upset: AC Milan win vs. Inter (+180 via FanDuel) ⭐⭐⭐⭐
  • Parlay: Elche vs. Villarreal: Villarreal to win, Over 1.5, and Gerard Moreno anytime goalscorer (+210 via BetMGM) ⭐⭐⭐

Top soccer picks

Total: Eintracht Frankfurt-Hertha Berlin Over 3.5 (+144) ⭐⭐⭐

Frankfurt sit sixth in the Bundesliga table and are in the chase for a Champions League spot, while the mood inside Hertha camp is rather different. They are now second from bottom, 17th, having lost all three matches since the German league returned after the winter break. Those three defeats saw Hertha concede 10 goals while scoring only once. 

Eintracht have seen over 2.5 goals being scored in five of their last six home games against Hertha in all competitions and will look to extend the prolific run when the Berlin side come visiting. And stats predict goals in this clash, with Hertha at the receiving end. They have conceded at least twice in five of their last six Bundesliga matches.

Spread: Napoli -1 vs. Spezia (+100) ⭐⭐⭐⭐

Napoli are 13 points clear of second-placed Inter in the Serie A table and will look to consolidate or even extend their lead after the trip to face Spezia. The home side is involved in a fierce relegation battle, so even a draw against Napoli would represent a huge bonus. There is little reason for optimism, though, as Spezia face in-form Napoli after losing three official matches in a row: 5-2 vs. Atalanta, 2-0 vs. AS Roma, and 2-0 vs. Bologna. 

Napoli -2 at +240 via BetMGM is also worth taking into consideration. Napoli -3 stands at an impressive +575 and might be an option for adventurous punters.

Upset: AC Milan win vs. Inter (+180) ⭐⭐⭐⭐

AC Milan have dropped to fifth in the Serie A following two heavy defeats: 4-0 vs. Lazio and 5-2 vs. Sassuolo. The defending champions find themselves in a horrible mood but that’s just a minor detail when it comes to playing a derby. A win over city arch-rivals Inter would make fans forget about the crisis. Inside the locker room, a derby win would surely serve as fresh inspiration as Milan look to climb the league ladder and finish in second position.

The fact that Inter are not in extraordinary form themselves could encourage Milan even more. A 1-0 home loss to Empoli was followed by a tough 2-1 triumph over bottom Serie A side Cremonese, so Inter manager Simone Inzaghi has many issues to address himself.

Elche vs. Villarreal Parlay: Villarreal to win, Over 1.5, and Gerard Moreno anytime goalscorer (+210) ⭐⭐⭐

Villarreal lost their previous match 1-0 vs. Rayo at home, affecting their push for Champions League football next season. If their intentions are serious, they can’t afford to make a step in the wrong direction when they travel to face the bottom La Liga club Elche. Elche are winless after 19 matches, winning just six points so far. They are 14 points behind safety, so their morale is in ruins.

Villarreal should be able to win this comfortably. Their star forward Gerard Moreno will also look to improve his season tally. Moreno only netted four times this season and is hungry to add more goals to his record.

Soccer odds and best bets from 2/2/2023 at 6:53 a.m. ET.

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