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NFL Odds Week 15: Lines & Spreads for Every Game

Andrew Reid

Last Updated: December 4, 2024 1:05 PM EST • 2 min 32 sec read.

Arizona Cardinals linebacker Mack Wilson Sr. breaks up the pass for Minnesota Vikings running back Aaron Jones as we look at the best NFL odds Week 15.
Arizona Cardinals linebacker Mack Wilson Sr. breaks up the pass for Minnesota Vikings running back Aaron Jones. Photo by Jeffrey Becker / Imagn Images.

2024 NFL Odds Week 15

(Odds via bet365)

GameSpread (Dec. 13)Moneyline (Dec. 13)Over/Under (Dec. 13)
Ravens vs. GiantsGiants +16.5Giants +90042.5 (-110/-110)
Bengals vs. TitansTitans +5Titans +19046.5 (-110/-110)
Cowboys vs. PanthersPanthers -2.5Panthers -15043 (-110/-110)
Chiefs vs. BrownsBrowns +4Browns +18043 (-110/-110)
Dolphins vs. TexansTexans -3Texans -15046.5 (-110/-110)
Jets vs. JaguarsJaguars +3.5Jaguars +14540.5 (-110/-110)
Commanders vs. SaintsSaints +7.5Saints +30043.5 (-110/-110)
Bills vs. LionsLions -2.5Lions -14054.5 (-110/-110)
Colts vs. BroncosBroncos -4.5Broncos -22044.5 (-110/-110)
Patriots vs. CardinalsCardinals -6Cardinals -26046 (-110/-110)
Steelers vs. EaglesEagles -5.5Eagles -26043 (-110/-110)
Buccaneers vs. ChargersChargers -3Chargers -15045.5 (-110/-110)
Packers vs. SeahawksSeahawks +2.5Seahawks +12546 (-110/-110)
Bears vs. Vikings Vikings -7Vikings -31044 (-110/-110)
Falcons vs. RaidersRaiders +4Raiders +17544.5 (-110/-110)
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The Week 15 NFL odds are out, and we have the first of four full slates to close out the season. Our NFL betting sites will have a busy week ahead reacting to betting patters and injury news that comes up throughout the week.

  • The Thursday Night Football odds opened with a Los Angeles Rams victory of the San Francisco 49ers, 12-6
  • The Sunday Night Football odds have the Packers as 2.5-point road favorites over the Seahawks in a game with major NFC playoff implications (8:20 p.m. ET, NBC/Peacock)
  • The Monday Night Football odds have a doubleheader
    • The Bears are nearly a full touchdown underdogs at the Vikings in an NFC North rivalry game (8 p.m. ET, ABC/ESPN+)
    • The Falcons' NFL playoff odds might be on the line as they look to snap a four-game losing skid when they visit the Raiders (8:30 p.m. ET, ESPN)
  • ATS leaders heading into Week 15: Steelers (10-3), Broncos (10-3), Lions (9-4), Chargers (9-4)
  • ATS losers heading into Week 15: Titans (2-11), Giants (4-9), Browns (4-9), Jets (4-9), Cowboys (4-9)
  • Over leaders heading into Week 15: Ravens (10-3), Panthers (9-4), Commanders (9-4), Bengals (9-4)
  • Under leaders heading into Week 15: Texans (4-9), Chargers (4-9), Giants (4-9)

Packers vs. Seahawks: Sunday Night Football 

  • Opening spread (Dec. 4): Seahawks +3
  • Opening moneyline (Dec. 4): Seahawks +130
  • Opening total (Dec. 4): Over/Under 46.5 (-110/-110)
  • Kickoff: 8:20 p.m. ET from Lumen Field (Seattle)
  • How to watch: NBC/Peacock

Bears vs. Vikings: Monday Night Football

  • Opening spread (Dec. 4): Vikings -5.5
  • Opening moneyline (Dec. 4): Vikings -245
  • Opening total (Dec. 4): Over/Under 42.5 (-110/-110)
  • Kickoff: 8 p.m. ET from U.S. Bank Stadium (Minneapolis)
  • How to watch: ABC/ESPN+

Falcons vs. Raiders: Monday Night Football

  • Opening spread (Dec. 4): Raiders +3
  • Opening moneyline (Dec. 4): Raiders +150
  • Opening total (Dec. 4): Over/Under 44.5 (-110/-110)
  • Kickoff: 8:30 p.m. ET from Allegiant Stadium (Las Vegas)
  • How to watch: ESPN

NFL Week 15 odds and lines

There's an advantage to betting the early NFL odds when attempting to beat the closing line. The closer you wait until kickoff to make your NFL picks, the harder it becomes to identify edges and secure the best price on most sides or totals.

That's why it's important to start monitoring the NFL opening odds each week as soon as possible. A proactive approach is the first step to long-term success.

NFL betting odds pages

Here are our best NFL betting sites:

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Written By:
Andrew Reid
Andrew is a Publishing Editor at Sportsbook Review. He graduated from Acadia University with a degree in Kinesiology, working as a personal trainer and in injury rehab, and then attended the College of Sports Media in Toronto to attain a diploma in Radio and Television Sports Broadcasting. Andrew has been involved in the sports betting and fantasy sports space since joining the FNTSY Sports Network in 2014, where he worked as a producer, director, and occasional on-air talent on various shows focusing on sports betting and DFS content. Prior to joining SBR, he spent multiple years with the USA Today Network as an editor and writer. Living in Newfoundland, Andrew frequents grey market sportsbooks, but in the past, when he's lived in regulated areas, he's become well-versed with all of our best sportsbooks. As strictly a casual bettor, he enjoys making touchdown parlays with friends (bro-lays), sweating out golf cut parlays during majors, playing same-game parlays for fun, and chasing long-shot bets. He also enjoys using sportsbooks that have solid iGaming and casino platforms. As the old guy on staff, he has an affinity for industry news, which confuses some, but shh ... quiet ... the news is on.