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Denver Broncos quarterback Bo Nix throws the ball as we offer our NFL Week 13 predictions and odds for this week.
Denver Broncos quarterback Bo Nix (10) throws the ball. Photo by Kirby Lee / Imagn Images.

Following the lightest week of the NFL season, we're offering our NFL Week 13 odds and predictions for a full 16-game slate with four games scheduled before Sunday - including three on Thanksgiving Day.

The action started Thursday with a classic NFC North rivalry between the Chicago Bears and the Detroit Lions. The latter entered this week as the Super Bowl odds favorites and one of two double-digit favorites in Week 13 but only escaped with a 23-20 win.

The other was the Kansas City Chiefs, hosting the Las Vegas Raiders. Those preceded a busy Sunday slate capped off by the Sunday Night Football odds clash between the San Francisco 49ers and Buffalo Bills at 8:20 p.m. ET (NBC).

The week concludes with the Monday Night Football odds showdown between the Cleveland Browns and the Denver Broncos to wrap up the NFL Week 13 odds.

NFL picks & predictions Week 13

Don't miss the rest of our Week 13 NFL picks. Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

NFL odds & predictions for Monday Night Football

Best Browns vs. Broncos odds

Prediction: Browns +6 (-108 via DraftKings) vs. Broncos ⭐⭐⭐⭐

  • When: Monday, Dec. 2 - 8:15 p.m. ET
  • Where: Empower Field at Mile High (Denver)
  • How to watch: ESPN

NFL picks roundup: Week 13

NFL betting odds pages

Here are our best NFL betting sites:

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