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NFL Week 12 Predictions 2024: Picks & Odds for Marquee Games

C Jackson Cowart

Last Updated: November 24, 2024 5:18 PM EST • 1 min 61 sec read.

Baltimore Ravens quarterback Lamar Jackson (8) is brought down as we offer our NFL Week 12 predictions and odds for this week.
Baltimore Ravens quarterback Lamar Jackson (8) is brought down by Los Angeles Chargers linebacker Tuli Tuipulotu (45). Photo by Gary A. Vasquez / Imagn Images.

Even with a smaller slate this week, we've seen a few surprises across our NFL Week 12 odds and predictions.

Sunday's slate featured 11 games, many of which ended as blowouts, though the lopsided result by the Sunday Night Football odds was still worth the price of admission with Saquon Barkley exploding onto the scene as an NFL MVP odds contender.

The NFL Week 12 odds conclude tonight with a family affair between the Baltimore Ravens and Los Angeles Chargers, which will mark the third-ever matchup between brothers John Harbaugh and Jim Harbaugh. The Ravens are favorites by the Monday Night Football odds with kickoff set for 8:15 p.m. ET on ESPN.

NFL picks & predictions Week 12

Don't miss the rest of our Week 12 NFL picks. Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

NFL odds & predictions for Monday Night Football

NFL odds via BetMGM and subject to change. Follow the latest NFL scores for line history and matchup info.  

Ravens vs. Chargers odds

Los Angeles Chargers quarterback Justin Herbert following victory as we offer our NFL Week 12 odds and predictions.
Los Angeles Chargers quarterback Justin Herbert following the victory against the Cincinnati Bengals. Photo by Gary A. Vasquez / Imagn Images.

Prediction: Ladd McConkey Over 5.5 receptions (+116 via FanDuel) ⭐⭐⭐

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Pick made by Mike Spector.

  • When: Monday, Nov. 25 - 8:15 p.m. ET
  • Where: SoFi Stadium (Inglewood, Calif.)
  • How to watch: ESPN
  • Moneyline: Ravens -160 | Chargers +135
  • Spread: Ravens -3 (-110) | Chargers +3 (-110)
  • Total: 50 (-110/-110)

NFL picks roundup: Week 12

NFL betting odds pages

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Written By:
C Jackson Cowart
C Jackson Cowart is a publishing editor and lead writer for Sportsbook Review. An award-winning writer, reporter, and editor with a decade of sports media experience, "C-Jax" has worked with ESPN, Forbes, theScore, and various daily newspapers before joining the Sportsbook Review team. He's a proud graduate of the University of North Carolina, where he served as a beat writer for the Tar Heels' championship run through the NCAA men's basketball tournament in 2017. Jackson has spent the last five years covering sports betting as a predictive analyst, features writer, and industry reporter. Since joining the team in 2023, he's played a key role in Sportsbook Review's coverage of the Super Bowl, March Madness, and NBA playoffs while serving as the lead writer for the growing WNBA and NASCAR betting scenes. Though he's cashed some big bets over the years -- including Lamar Jackson to win MVP (twice) -- he's still haunted by enough second-place bet slips to wallpaper his home office. While Jackson is a committed "process over results" bettor with a keen eye for advanced stats and subtle bias in futures markets, he also embraces sports betting as a vehicle for entertainment and personal investment. He's written about everything from hot dogs to groundhogs and still hasn't forgiven his "inside source" for a sabotaged bet on the Gatorade color in Super Bowl LV.