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Vikings vs. Eagles Predictions, Picks, Odds Week 2: Thursday Night Football

Mike Spector

Last Updated: September 14, 2023 6:16 PM EDT • 4 min 47 sec read.

As the Minnesota Vikings and Philadelphia Eagles clash on Thursday Night Football to open the NFL's Week 2, we have you covered with our best Vikings-Eagles prediction based on the best NFL odds.

Minnesota's inevitable regression was evident after their remarkable 11-0 record in one-possession games last year. This regression materialized right from the start of the season, with the Vikings suffering a 20-17 defeat at home against the Tampa Bay Buccaneers. In the late stages of the game, the Vikings struggled to generate any momentum, as their last two drives consisted of merely six plays, accumulating a mere six yards in total.

Meanwhile, Philadelphia is trying to avoid the dubious fate of many Super Bowl losers from the previous season, as 17 of those 56 teams missed the playoffs the following year. However, the Eagles passed their first test in Week 1 with a 25-20 road victory over the New England Patriots and improved to 3-0 in season openers under head coach Nick Sirianni.

Here is our best Vikings vs. Eagles prediction for Thursday Night Football, which is also accompanied by our Vikings vs. Eagles player props and Thursday Night Football player props (odds via our best NFL betting sites; pick confidence based on a 1-to-5-star scale).

Vikings vs. Eagles prediction: Thursday Night Football

Eagles -7 () ⭐⭐⭐

Minnesota is likely regretting not taking advantage of the opportunities it had in the first half to accumulate a bigger lead against Tampa Bay, as it out-gained the Buccaneers 287-96 over the first 30 minutes. However, three first-half turnovers thwarted any momentum.

The Buccaneers allowed 11 first downs in the first half, and Vikings wide receiver Justin Jefferson torched them for seven catches and 138 yards. However, after halftime, Tampa Bay allowed just 82 total yards and seven first downs, and held Jefferson to 12 yards on two receptions. We're looking at our best Justin Jefferson player props expecting a bounce-back performance.

If Minnesota can't generate a more consistent running game, which was always going to be an issue after losing Dalvin Cook, its offense will have trouble moving the ball. Vikings running backs totaled just 34 yards on 14 carries, with Alexander Mattison running for more than five yards just twice.

Minnesota’s offensive line woes go deeper than run blocking, as the unit ranked dead-last in quarterback hits allowed and allowed pressure on 23.3% of dropbacks, per . That is scary when entering a matchup with an Eagles defense whose 70 sacks last season were tied for the third-most in NFL history and who ranked first in the league in Pass Rush Win Rate.

Given how much last week’s game against the Buccaneers turned on its head once they shut down Jefferson, that is also concerning, considering Philadelphia’s cornerback tandem of Darius Slay and James Bradberry is arguably the best in the NFL, while its secondary as a whole was ranked third by .

The Eagles barely covered as 3.5-point favorites against the Patriots last week, and they're now a touchdown favorite in our NFL Week 2 odds and betting lines. Still, one must consider that they faced arguably the best coach of all time, who had a whole offseason to prepare for their unique offensive attack. It was also their first game after losing their offensive and defensive coordinators from last year’s team.

Philadelphia’s most significant edge on the offensive side will be on the outside with its wide receiving tandem of A.J. Brown and Devonta Smith. Minnesota’s defense against wide receivers last season ranked last in passing yards per game (192.1), 31st in QBR (84), and 29th in completion percentage (67%). However, if the new Brian Flores-led defense plays it cautiously to respect Philadelphia’s big-play passing ability, a running game that ranked second with a 74.9% run-block win rate and produced an NFL record 42 rushing touchdowns will dictate how the game is won.  

Esten McLaren's anytime touchdown scorer prediction for Thursday targets the Eagles' rushing game.

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Vikings vs. Eagles best odds

DraftKings FanDuel BetMGM Caesars bet365
-7-7 -7 -7
-112-110 -110 -110

All five of our best sports betting apps are in unison with the 7-point spread, but  is the only one charging less than standard -110 juice on either side. It is somewhat surprising to see DraftKings charging less in juice to back the 1-0 team on the point spread as opposed to the team that lost last week, and this line is much higher than the -3 point spread in this meeting last year when the Eagles beat the Vikings 24-7 at home in Week 2.

Vikings vs. Eagles odds for Thursday Night Football

Vikings vs. Eagles odds analysis

Caesars’ lookahead line for this game in mid-August was Eagles -6, but all of our best sports betting sites opened with higher than a touchdown spread once the Week 1 results were known. FanDuel and BetRivers were the only shops that ever got as high as +8 on Monday morning, but those lines did not last long, as Vikings backers weighed in and drove the number down to +7.5, where all sportsbooks stayed for much of Monday morning. Sharp action likely took this spread down from -7.5 to -7, as 80% of the wagers are on the Eagles, representing significant reverse line movement.

Similar to the point spread, there is no discrepancy on the 48.5-point total across our best sportsbooks, though BetRivers is the only one juiced to the Under at -115. DraftKings is already down from an opening number of 49, while all others have stayed more consistently at 48.5 through Monday.

Moneyline backers may not scoff at Philadelphia’s -290 odds at DraftKings (the high end is BetMGM at -350), as Eagles quarterback Jalen Hurts has won 18 of his previous 19 regular season starts. For action on Hurts, see our Jalen Hurts player props.

Thursday Night Football game info

  • When: Thursday, Sept. 14 at 8:15 p.m. ET
  • Where: Lincoln Financial Field, Philadelphia, PA
  • How to watch: Prime Video
  • Weather: 57 degrees, 2% chance of precipitation, wind 9 mph N

Vikings-Eagles prediction made 9/12/2023 at 6:39 a.m. ET

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Written By:
Mike Spector
Mike started in the sports writing industry in July 2019, and gained a lot of followers in his first year after finishing with the No. 2 overall record in an annual NFL betting competition, which made picks against the spread, and from an Over/Under and moneyline perspective. Mike is an avid fan of the NFL, MLB, tennis, and all college sports. In his opinion, March Madness is the best sporting event there is, and he's especially euphoric starting with conference tournament time in college basketball. Mike's a big advocate of "fading the public" and making plays that are contrarian, constantly citing that "there are reasons why they have those big shiny buildings in Las Vegas." When making wagers, Mike always scours the best odds at all of the major sports betting sites, where he mostly sifts through DraftKings, FanDuel, BetMGM, and bet365. He's tried several others and is of the firm belief that bettors should not just stick to one sportsbook, as there is always likely better value to be had with the same wager. In addition, while Mike received his undergraduate degree from Villanova University, he has no issue betting against the Wildcats when it comes to college basketball wagering, and suggests other bettors should always put their “head” before their “hearts.”