NFL Upset Picks, Predictions Week 8: 3 Underdogs to Bet This Week

NFL underdogs won five games outright last week, and the ‘dogs will look to continue barking throughout Week 8’s loaded 16-game slate.

• Five underdogs won outright in Week 7, but none of the top eight moneyline favorites lost
• Six of this week’s 16 games have point spreads of a field goal or less
• There are five games between divisional opponents, and the road team is favored in four

Our NFL upset picks involve three road underdogs, with our biggest upset pick coming in a divisional game where just two points decided their first tilt.

The underdog picks are part of our NFL Week 8 predictions. 

NFL underdogs to back: Week 8

NFL odds as of Wednesday and subject to change. Track the NFL scores for the latest line movement and matchup info.

• Eagles () at Bengals ⭐⭐⭐⭐
• Cardinals () at Dolphins ⭐⭐⭐
• Colts (+225 via BetMGM) at Texans ⭐⭐⭐

Week 8 upset predictions

NFL picks made Wednesday; odds subject to change. Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Eagles (+130) ⭐⭐⭐⭐

The Bengals have seemingly hit their stride, with consecutive wins for the first time this season and wins in three of their last four.

However, the three teams they have beaten are a combined 4-17. That makes the Eagles, who are also amid their first two-game winning streak, live underdogs.

Philadelphia, among the Super Bowl odds favorites, is the healthiest it has been all season, and it improved to 3-0 when A.J. Brown is active.

Brown has 80-plus receiving yards and a touchdown in all three games. He serves as a great complement to Saquon Barkley and the running game, as Barkley’s 176 yards rushing against the Giants were the second-most all-time by a player against his former team.

Cincinnati was happy to snap its six-game losing streak at Cleveland last week, but it went 0-for-6 on third downs in the first half. That will not cut it against an Eagles offense that can score among the best of them when healthy.

BetMGM is one of our only best sports betting sites offering better than +125 odds to back the underdogs. With the generous +130 odds, a $10 winning wager would net $13 in profits.

If you want some more action on this one, Philip Wood's Eagles vs. Bengals player prop bets offer a great trio of plays.

Best odds: +130 via BetMGM | Implied probability: 43.48%

Cardinals (+145) ⭐⭐⭐

The Dolphins being favored by three points in this matchup comes with the news that Tua Tagovailoa is prepared to return as starting quarterback.

If that is the case, I am still willing to fade the Dolphins, as there is no telling how Tagovailoa will acquit himself after suffering another severe concussion.

For the first time since 2007, the Dolphins have scored 15 or fewer points in five consecutive games and have three touchdowns in 51 possessions since their starting quarterback’s injury. Philip Wood dives into Tua's return in his Tua Tagovailoa player prop bets. 

Arizona is coming off an impressive Monday night victory against the Chargers and is not being given enough credit. 

I am making my $10 wager at bet365, the only one of our best NFL betting sites offering better than +143 odds, hoping to net a $24.50 payout.

Best odds: +145 via bet365 | Implied probability: 40.82%

Colts (+225) ⭐⭐⭐

Indianapolis’ 27 points in the 29-27 Week 1 loss to the Texans are tied for its second-highest scoring output of the season.

While the Colts had defensive issues in that game, they should be encouraged by Anthony Richardson and the passing game's three completions of 50 or more yards.

The Colts allowed 213 rushing yards in that game, their most since Week 17 of the 2022 season. But their pass rush was dominant, pressuring C.J. Stroud on 38% of his dropbacks and sacking him four times.

Indianapolis has won four of five games since starting 0-2, and its 4-3 start is the best since 2020.

While its four wins are by 18 total points and each win has been by six or fewer, it is encouraging that the Colts find ways to prevail in close ones more often than not

Mike Spector dives deep on his Colts vs. Texans player props.

There is a big 20-cent difference between BetMGM’s +225 odds and the +205 odds offered at DraftKings, which carry a 32.79% implied probability.

Best odds: +225 via BetMGM | Implied probability: 30.77%

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