NFL Picks, Predictions Roundup Week 16: Best Bets for Christmas Eve and Christmas Day

The NFL largely gives way to the NBA on Christmas Day but there are still three games on the docket before Monday Night Football. Check out our top NFL picks for Week 16.  

Our NFL betting experts have been tracking the odds and lines for Week 16, and they offer their top ATS, O/U, and prop plays for the week below. Be sure to check out our NFL ATS power rankings, teaser picks, upset picks, trends to know, Over/Under picks, touchdown scorer prop picks, Christmas Day parlay picks. and Week 16 best bets.

All season we'll also be keeping an eye on the odds to win the 2023 Super Bowl and each of the major NFL awards.

NFL Picks Week 16: Monday

Chargers vs. Colts Picks

Best bet: Over 45 (-110 via DraftKings)

Top Week 16 NFL Picks

• Week 16 Odds and Lines
• Week 16 Best Bets
• Christmas Day Parlay picks
• Christmas Day Prop picks
• Touchdown Scorer Picks
• Against the Spread Power Rankings
• Teaser Picks
• Upset Picks
• Trends to Know
• Over/Under picks

Here are our Best NFL Betting Sites:

Check out our Best NFL Betting Sites:

• FanDuel: Get a | Read our FanDuel Review
• Caesars: Earn a | Read our Caesars Review
• DraftKings: Get a | Read our DraftKings Review
• PointsBet: Earn | Read our PointsBet Review
• BetMGM: Get a | Read our BetMGM Review

* Bonuses not applicable in Ontario.

Related Pages

U.S. Sports Betting | Best U.S. Sportsbook Promos