Jets vs. 49ers Odds, Early Leans & Picks: How to Bet New York vs. San Francisco

We're less than a week away from the first Monday Night Football matchup of the season between the San Francisco 49ers and New York Jets - two of the top teams by the latest Super Bowl odds.

Entering Week 1, the 49ers are favored by 3.5 points to beat the Jets, who were catching nearly a touchdown by the opening Monday Night Football odds before heavy action on Gang Green.

San Francisco is still the team to beat by the NFL Week 1 odds, but New York is clearly the trendy pick as we offer our Jets vs. 49ers odds and early leans as part of our NFL Week 1 predictions.

Jets vs. 49ers odds

See the NFL odds from our best NFL betting sites for every Week 1 game.

Moneyline

• 49ers best odds: | Implied probability: 65.52%
• Jets best odds: | Implied probability: 37.59%

If you like the Jets' chances of winning this game, you're running out of time to grab the best value. New York is still dealing as high as +166 to win on Monday, which would pay out $16.60 on a $10 wager, but that's a far cry from an opening price of +225 via BetMGM.

Spread

• 49ers best odds:
• Jets best odds:

As we mentioned earlier, the 49ers opened as nearly touchdown favorites in May before a rush of action on the Jets, who could conceivably close at +3 if that continues. Given the current pricing on the spread, it seems like this line could be moving back toward 4 before kickoff.

Over/Under

• Over best odds:
• Under best odds:

We've seen this total dip slightly in recent weeks, and I wouldn't be surprised if that continues with Trent Williams (holdout) uncertain for Week 1. You can still find some value by shopping across our best sports betting sites, which have this total between 43 and 43.5.

My early Jets vs. 49ers lean

NFL picks made Monday; odds subject to change.

Prediction: 49ers -3.5

Best odds: | Implied probability: 52.38%

I get the hype around New York, which should finally have its chance at a Super Bowl run with a healthy Rodgers.

What I don't get is how the market views the Jets as virtually even with the 49ers on a neutral field. Williams' absence is a concern, though fellow holdout Brandon Aiyuk is back with the rest of this star-studded core that tore through the league last year.

If Williams doesn't suit up, I might lean toward the Under over anything else, but I'll hold off on buying into Gang Green mania until we see some actual results on the field.

Don't miss our guide for how to bet on NFL or this week's best sportsbook promos.

How to watch Jets vs. 49ers

• When: Monday, Sept. 9
• Kickoff: 8:15 p.m. ET
• Where: Levi's Stadium (Santa Clara, Calif.)
• How to watch: ABC/ESPN
• Weather: 80 degrees, 0% chance of precipitation, wind 13 mph
• Favorite: 49ers -3.5 (-110 via BetMGM)

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