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We're offering up our top NFL picks and predictions as the Cleveland Browns shoot for a rare 2-0 start with a home date against the 0-1 New York Jets in Week 2.

The Browns spoiled Baker Mayfield's debut with the Carolina Panthers with a 26-24 road win in Week 1. The was the organization's first season-opening win since 2004 with backup quarterback Jacoby Brissett leading the way.

The Jets once again face the challenge of sparking their offense in the absence of injured quarterback Zach Wilson. They stumbled to a lopsided 24-9 season-opening loss to the rejuvenated Baltimore Ravens. Veteran Joe Flacco draws another start after throwing for 309 yards but with just one touchdown and one interception last week.

Here are our top Jets-Browns NFL picks for Week 2 (odds via PointsBet and FanDuel Sportsbook; pick confidence based on a 1-to-5-star scale).

Jets vs. Browns Game Info

Date: Sunday, Sept. 18, 1 p.m. ET
TV: CBS
Location: FirstEnergy Stadium, Cleveland, OH
Weather: Mainly sunny, 82 degrees, 20% chance of precipitation, 9-mph winds 

Jets vs. Browns Odds Analysis

The Over/Under has plummeted from an opening line of 43.5 to 39.5. While bettors are now getting the worst of the number, the Under has drawn 80% of the handle on 64% of the tickets.

Bettors are also backing the Browns with a slight majority of both the handle and the tickets. Cleveland remains a 6.5-point favorite with 63% of the tickets and 54% of the handle.

Jets vs. Browns Picks

Browns915

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Jets vs. Browns ATS Pick

Browns -6.5 (-107) ★★★★

Veteran QB Jacoby Brissett skillfully used all the offensive weapons at his disposal to lead the Browns to a 26-24 win over Carolina last week. In addition to racking up 147 passing yards and one TD, Brissett guided the Browns on a late drive that resulted in a game-winning field goal. 

The Browns' defense harassed Mayfield all day. The result was four sacks, four fumbles, and one interception. With Jets quarterback Joe Flacco struggling in all departments and lacking in mobility, and injuries to offensive tackle George Fant and receiver Braxton Berrios, expect the Browns to have another huge day defensively.

Check out the latest comprehensive and most trusted Sportsbook Reviews by SBR.

Jets vs. Browns O/U Pick

Over 39.5 (-106) ★★★

The Jets offense failed to penetrate the Ravens' red zone last week until well into garbage time. Points are likely to come at a premium once again on Sunday. However, there is little reason to expect the Browns' attack to falter against a hobbled Jets defense that seemed powerless to contain the Ravens last week, even in rainy conditions. 

Jets vs. Browns Prop Pick

Chubb Over 82.5 rushing yards (-110) ★★★★

Brissett leaned heavily on running back Nick Chubb last weekend in Carolina, and the Browns rusher obliged by piling up 141 yards on 22 carries. He has now run for 83 or more yards in seven of eight September contests in his career.

That trend should continue against a Jets defense that ranked 29th in the NFL against the run last season, and which will likely enjoy little rest against a methodical and relentless Browns attack.

Where to Bet on Jets vs. Browns Picks

Here are our top-rated sportsbooks:

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Jets-Browns picks made 9/15/2022 at 3:26 p.m. ET