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Jacksonville Jaguars wide receiver Brian Thomas Jr. scores a touchdown against the Indianapolis Colts. We're backing Jacksonville in our Jaguars vs. Bears prediction.
Jacksonville Jaguars wide receiver Brian Thomas Jr. scores a touchdown against the Indianapolis Colts. Photo by Nathan Ray Seebeck via Imagn Images.

With both teams coming off wins, the Jacksonville Jaguars and Chicago Bears meet in London in the second NFL International Series game of the year.

  • Despite being 3-2, the Bears have the longest Super Bowl odds in the NFC North
  • Caleb Williams is coming off his best game of the season and trails just Jayden Daniels in the NFL Offensive Rookie of the Year odds race
  • Nobody plays in London more than the Jaguars, who are 6-5 across the pond since 2013

As part of our Week 6 NFL predictions, our Jaguars vs. Bears prediction expects Jacksonville to have a second straight strong showing.

Read on for more of why we like the Jaguars to cover in our NFL upset picks for Week 6. We went 2-0 with our two London picks last week, and are back to continue the momentum in Week 6.

Jaguars vs. Bears odds movement

The Bears opened as a 1.5-point favorite at our Super Bowl betting sites The line has since moved a half-point with the Bears just -1 in London.

The Bears have 62% of the money on them covering, with just 38% on the Jaguars. The Over has 53% of the money, with the total hovering around 44.5.

Best Jaguars vs. Bears picks

NFL picks based on the odds from our best NFL betting sites. Odds subject to change.

  • Against the spread pick: Jaguars +2 () vs. Bears ⭐⭐⭐⭐
  • My best bet: Travis Etienne Jr. Under 44.5 rushing yards () ⭐⭐⭐⭐

Jaguars vs. Bears against the spread prediction: Week 6

Jaguars to cover the spread: +2 (-105) ⭐⭐⭐⭐

Jaguars vs. Bears opening odds:

  • Jaguars: +1.5 (-110 via BetMGM)
  • Bears: -1.5 (-110 via BetMGM)

Jacksonville will feel more at home

Trevor Lawrence is making his fourth start in London since his rookie season in 2021 and has led the team to a 3-1 record in those games. Last season, the Jaguars played games in back-to-back weeks in London in early October, which led to more rumors about owner Shahid Khan’s plans to move the team there permanently. Regardless, the extended travel and the time difference are real, and no team is more used to that and equipped to handle it than Jacksonville.

Bears are unproven away from home

Chicago is one of four NFC North teams with a winning record entering this week. The Bears owe a lot of that early success to a favorable schedule that saw them play three home games to this point.

The Bears are amid their longest home winning streak (eight games) since 2005-06. They are coming off their largest margin of victory (26 points) since Week 17 of the 2021 season, and Caleb Williams is now the first rookie quarterback to win his first three career home starts since Brock Purdy in 2022.

At home this season, Williams is 3-0 with three touchdowns and zero turnovers. But in the two road games, he is 0-2 with a 2-4 TD-INT ratio and five total turnovers, producing a 31.2 Total QBR or worse in both starts. Until Williams and the Bears show they can play better away from home, I will continue to fade them in those spots.

Lawrence can play more freely

Week after week, Trevor Lawrence could not avoid questions about “the losing streak,” as he entered last week having lost nine consecutive starts. However, now that he has the “monkey off his back” after throwing for 371 yards and leading the Jaguars to a 37-34 win over the Indianapolis Colts last week, I expect the offense and the team as a whole to continue to make strides. 

Given that the Jaguars have only scored 21-plus points once this season, they may have to win a slugfest this week. However, the team has allowed 21 or fewer points in each of their last four London games, so I expect them to be comfortable in what could be another defensive struggle. Our Philip Wood broke down the slugfest in his Jaguars vs. Bears early picks.

At one point earlier this week, all of our best sports betting apps were in unison with the Bears -2.5. However, several of our top sports betting sites have since lowered to -1.5, so the best number and price remains at Caesars, the only sportsbook where one can back the underdogs at +2 with odds better than the standard -110 juice.  

A winning $10 wager would pay out $19.52.

Best odds: -105 via Caesars | Implied probability: 51.22%

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Jaguars vs. Bears best bet

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Travis Etienne Jr. Under 44.5 rushing yards (-110) ⭐⭐⭐⭐

Over the last two weeks, Jaguars head coach Doug Pederson and the rest of the offensive coaching staff have made running back Tank Bigsby more of a focal point of the team’s rushing attack, which makes Etienne Jr.’s rest of the season outlook a bit murky.

Etienne has a 37.0% team rush share in the last two games and has averaged 4.4 yards per carry this season. Meanwhile, Bigsby has been the more explosive runner with an 8.0 yards per rushing attempt average, and the team has fed into that potential by affording him a 43.5% rush share the last two weeks. 

Chicago’s run defense entered last week ranked in the top 11 in lowest missed tackle rate and yards after contact per attempt allowed. Plus, with Lawrence coming off his best game of the season after completing two passes of 61-plus yards last week, I look for Jacksonville to feed that momentum with a heavier pass game than usual.

Etienne’s O/U is as low as 41.5 at FanDuel, and the juice at BetMGM is -120 to back the Under of 44.5. Thus, the best price and number are at bet365.

Best odds: -110 via bet365 | Implied probability: 52.38%

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Jaguars vs. Bears odds

See all of this week's NFL odds and NFL scores.

Jaguars vs. Bears game info

  • When: Sunday, Oct. 13
  • Kickoff: 9:30 a.m. ET
  • Where: Tottenham Hotspur Stadium, London
  • How to watch: NFL Network
  • Weather: 46 degrees, 20% chance of precipitation, wind 6 mph SE
  • Favorite: Bears -1.5 (-120 via BetMGM)

NFL betting odds pages

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