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Buccaneers vs. Saints Picks, Predictions NFL Week 2: Tampa Bay Visits Big Easy as Narrow Favorite

Daniel Coyle

Last Updated: September 20, 2022 11:01 AM EDT • 2 min 10 sec read.

The New Orleans Saints look to begin the season with a second straight win over an NFC South rival. Here are our top picks as the Saints host the 1-0 Tampa Bay Buccaneers.

The Buccaneers soundly beat the lifeless Dallas Cowboys 19-3 on Sunday Night Football in Week 1. Earlier in the day, the Saints came from behind to drop the Atlanta Falcons with a 27-26 road win. The Bucs and Saints finished first and second, respectively, in the NFC South last week but both have a new head coach this season.

Here are our top Buccaneers-Saints NFL picks for Week 2 (odds via Pointsbet and FanDuel Sportsbook).

Buccaneers vs. Saints Game Info

Date: Sunday, Sept. 18, 1 p.m. ET
TV: FOX
Location: Caesars Superdome, New Orleans, LA
Weather: Indoors

Buccaneers vs. Saints Analysis

The Buccaneers have dropped from 4-point to 2.5-point favorites. While injuries for Tampa Bay have played a role in that, the betting support is also with New Orleans. The Saints have drawn 59% of the handle on just 45% of the tickets.

Similarly, the Over has been the pick on 56% of tickets but those picks account for just 39% of the handle on the Over/Under. The line has dropped from 46.5 to 43.5.

Buccaneers vs. Saints Picks

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Buccaneers vs. Saints ATS Pick

Buccaneers -2.5 (-112) ★★★★

Tampa Bay quarterback Tom Brady and the Bucs silenced preseason doubters with an impressive primetime victory in Dallas last weekend. While it took the defending NFC South champs until the second half to find the end zone, they dominated offensively, recording field goals on four of their first five possessions.

Tampa Bay's defense also came up big against the vaunted Cowboys attack, not allowing Dallas to march inside the 40-yard line after surrendering a field goal on the Cowboys' first possession. With the dress rehearsal in the books, look for this offense to generate points Sunday.

Check out the latest comprehensive and most trusted Sportsbook Reviews by SBR.  

Buccaneers vs. Saints O/U Pick

Over 44.5 (-110) ★★★

High-scoring clashes between these two teams are nothing new. While the Under is 3-1 in their past four meetings, the total hit at least 50 points twice during that stretch, and in seven of their past 10 clashes.  

Buccaneers vs. Saints Prop Pick

Brady Over 1.5 TD passes (-180) ★★★

Brady flashed midseason form in Week 1, connecting on 18 of 27 pass attempts including a five-yard TD pass to receiver Mike Evans in the third quarter to put the game out of reach. No. 12 must still contend with injuries to his receiving corps, including Evans, Julio Jones, and Chris Godwin. However, New Orleans' secondary is also dealing with its own wounded, most notably cornerbacks Paulson Adebo and Alontae Taylor.

Considering the overall struggles the Saints faced containing an inferior Atlanta attack in last week’s comeback win, they have work to do to keep Brady out of the end zone.

Where to Bet on Buccaneers vs. Saints Picks

Here are our top-rated sportsbooks:

SEE ALSO: All picks, odds, and sports betting news. Be sure to check out 520ccc.com’s community forums and betting tools.

Buccaneers vs Saints picks made 09/15/2022 at 6:47 p.m. ET

Written By:
Daniel Coyle
An award-winning writer based in Montreal, Quebec, Daniel Coyle has covered sports and sports betting for major mainstream and online publications for over two decades. A passionate hockey fan, Daniel has covered a wide array of major sports leagues including the NHL, NFL, NBA, UFC, Formula 1, and US college sports. Daniel has also told the stories of Indigenous athletes from across Canada, and the important role sports play in First Nations communities.