Brock Purdy Picks, Predictions & Best Bets for Thursday Night Football Week 15

After Josh Allen ate the Los Angeles Rams alive in the Week 14 shootout on Sunday afternoon, we can see the San Francisco 49ers throwing all over the Los Angeles defense on Thursday night.

Our Brock Purdy picks and predictions based on our best Thursday Night Football odds see another productive passing day in store for the San Francisco quarterback. Our Mike Spector makes his Thursday Night Football prediction, could Purdy impact the outcome?

The 49ers take on the Rams at Levi’s Stadium in Santa Clara, Calif. Kickoff is set for 8:15 p.m. ET (Amazon Prime Video) with the hosts listed as 2-point favorites with our best NFL betting sites.

Brock Purdy TNF player prop picks

NFL odds as of Thursday and subject to change. Track the NFL scores for the latest line movement and matchup info.

• Brock Purdy prop pick: Over 250.5 passing yards () ⭐⭐⭐⭐⭐
• Brock Purdy prop pick: Over 1.5 passing touchdowns () ⭐⭐⭐⭐
• Brock Purdy prop pick: Over 18.5 rushing yards (-110 via FanDuel) ⭐⭐⭐⭐

Brock Purdy prop picks

NFL picks made Thursday; odds subject to change. Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Brock Purdy Over 250.5 passing yards ⭐⭐⭐⭐⭐

Brock Purdy racked up 325 passing yards on the Chicago Bears last week in a resurgent effort for the San Francisco offense. We like Purdy to stay in the flames on Thursday — and his passing line feels extremely attainable across our best sports betting sites.

• Even in this up-and-down season for the 49ers offense, Purdy has cleared a 250.5-yard passing line in seven of 12 games
• The Rams allow 224.7 passing yards per game (23rd in the NFL)
• Los Angeles gave up 345 passing yards to Josh Allen last week
• In his first matchup against the Rams this season, Purdy piled up 292 passing yards

With the line set at 250.5 yards at BetMGM and DraftKings, this is one of my favorite props of the NFL season.

Best odds: -115 via BetMGM | Implied probability: 53.49%

Thursday Night Football picks

• Rams vs. 49ers prediction
• Rams vs. 49ers TNF prop bets
• Rams vs. 49ers parlay picks
• Puka Nacua picks, predictions & best bets
• Anytime touchdown scorer predictions
• First touchdown scorer predictions

Brock Purdy Over 1.5 passing touchdowns ⭐⭐⭐⭐

With the prediction for Purdy to rack up yards through the air, we like him to light it up in the scoring department too.

• The Rams have allowed multiple passing touchdowns seven times in 13 games
• Out of seven games where Purdy has cleared Thursday’s passing yardage line, he’s thrown for multiple touchdowns four times
• Purdy threw three touchdowns the first time he faced the Rams this season

Target FanDuel for this prop, with -120 odds on Over. FanDuel has the best odds among the NFL prop betting sites for this play, whereas other sportsbooks carry odds between -140 and -147.

Best odds: -120 via FanDuel | Implied probability: 54.55%

Brock Purdy Over 18.5 rushing yards ⭐⭐⭐⭐

While we’re not crazy about this line being as high as it is, we’re leaning into the Rams’ deficiencies against mobile quarterbacks lately by taking the Over on Purdy’s rushing prop.

• Josh Allen, Jalen Hurts and Drake Maye have all cleared this line against the Rams in recent weeks
• Purdy has hit this mark in 50% of his game this season (six out of 12)
• He ran 10 times for 41 yards against Los Angeles earlier in the year

The FanDuel line at 18.5 yards is the one to target for Over bettors, as the rest of the best sports betting apps list the line at 20.5 yards.

Best odds: -110 via FanDuel | Implied probability: 52.38%

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