In a rematch of the regular-season finale, Louisville (25-6) and Stanford (20-12) will square off in the ACC quarterfinals at 7 p.m. ET tonight at Spectrum Center.

The Cardinal hope it isn’t a repeat from last Saturday’s showing, when they suffered a 68-48 loss to the Cardinals. Louisville is a 10.5-point betting favorite in the postseason rematch on ESPN2.

Check out our Stanford vs. Louisville prediction, odds, and expert picks for tonight’s ACC quarterfinal showdown.

💰 Stanford vs. Louisville predictions, expert picks & best bets: ACC Quarterfinal

Here are my best Stanford vs. Louisville predictions, expert picks, and best bets today for the ACC quarterfinal with my pick confidence based on a 1-to-5-star scale. Be sure to check out the rest of our college basketball picks along with our guide on how to bet on college basketball.

• Against the spread pick: Louisville -6.5 first half (-105 via Caesars) vs. Stanford ⭐⭐⭐⭐
• My best player prop bet: Chucky Hepburn Under 1.5 made 3-pointers (+100 via BetMGM) ⭐⭐⭐
• Exact score prediction: Louisville 79, Stanford 66 (+13000 via DraftKings)

👉 Check out our latest March Madness projections with our SBR Bracketology ahead of the NCAA Tournament!

🏀 Stanford vs. Louisville ATS prediction & best player prop bet pick

Here's why I'm betting on Louisville to cover the first-half spread (-6.5) while targeting Chucky Hepburn Under 1.5 made 3-pointers as my best player prop bet pick for today:

✅ Louisville to cover the spread in first half (-6.5) ⭐⭐⭐⭐

Pinnacle - one of the best trading teams in the industry - has a 6-point spread in the first half, so it could be worth waiting for a better number. But Louisville is a team worth backing out of the gates, as it ranks 11th in the nation with a first-half rating of 11.1 via Team Rankings.

The Cardinals allow 30.5 points per game in the first half, so their 19th-ranked defense often sets the tone. Louisville held Stanford to 18 points in the first half last weekend, jumping out to a 15-point lead at the break.

The spread has remained the same for tonight’s rematch, so I’m happy to back Louisville in this market.

📊 Best odds: -105 via Caesars (bet $10 to win $9.52)

🔥 Chucky Hepburn Under 1.5 made 3-pointers ⭐⭐⭐

Louisville guard Chucky Hepburn missed all five 3-point attempts last Saturday against Stanford.  

The Cardinal do a solid job of limiting 3-pointers, allowing 33.8% of all field goal attempts to be from long range. For context, that mark ranks 28th in the nation, and the average is 39%.

Hepburn has hit multiple triples in three of his past five games, but I’ll take the plus-money price that he doesn’t do it in a potential blowout.

📊 Best odds: +100 via BetMGM (bet $10 to win $10)

🎯 Expert Stanford vs. Louisville score prediction & AI projections

🔮 Expert score prediction: Louisville 79, Stanford 66
🤖 AI score prediction: Louisville 74, Stanford 60

🔮 Expert score prediction: Louisville 79, Stanford 66

The Cardinals should control this game from start to finish after having four days off since playing the same opponent. Stanford is coming off a 78-73 win over California last night, but has only one win against a top-100 team on KenPom since late January.

📊 Best odds: +13000 via DraftKings (bet $10 to win $1,300)

🤖 AI score prediction: Louisville 74, Stanford 60

(Score prediction and analysis via ChatGPT - a large language model from OpenAI. While ChatGPT is not specifically designed for predicting sporting events, it can spot trends or insights that bettors might overlook.)

🖥️ AI predictions for Stanford vs. Louisville

The projected final score for tonight’s ACC quarterfinal matchup is Louisville 74, Stanford 60.

• Win probability: Louisville 83%, Stanford 17%
• Projected total points: 134

🤔 Betting takeaway: ChatGPT's AI score prediction leans toward Louisville covering the spread (-10.5) and a total of Under 144.5 points.

📊 Live Stanford vs. Louisville odds & latest betting splits

Here are the latest odds for Stanford vs. Louisville, which update live in real time. You can also check out our NEW college basketball player prop odds tool for the latest college basketball odds on any market across legal sportsbooks in your region.

🔢 Stanford vs. Louisville opening odds

Here's a look at the opening odds for Stanford vs. Louisville, according to BetMGM.

• Spread: Stanford +10.5 (-110) | Louisville -10.5 (-110)
• Moneyline: Stanford +400 | Louisville -550
• Over/Under: Over 144.5 (-110) | Under 144.5 (-110)

🏆 Who will win Stanford vs. Louisville?

As of 10:30 a.m. ET, Louisville is favored by 10.5 points to beat Stanford with moneyline odds of -650 at BetMGM, which suggests an 86.67% win probability for the Cardinals. We're predicting a 79-66 win for Louisville as our final score projection.

📺 How to watch Stanford vs. Louisville tonight

📅 Date: Thursday, March 13
🕗 Time: 7 p.m. ET
📍 Location: Spectrum Center (Charlotte)
📺 TV: ESPN2
💻 Streaming: ESPN+

❓ Stanford vs. Louisville FAQs

Who's favored to win the ACC Conference tournament?

Duke is favored to win by the latest ACC Tournament odds.

Who is favored to win Stanford vs. Louisville?

Louisville is a -650 favorite, for an implied probability of 86.67%.

What are the betting odds for Stanford vs. Louisville

The latest spread is Stanford +10.5 (-105) | Louisville -10.5 (-115), with a total of 144.5 points (-110).

What will be the final score of Stanford vs. Louisville?

We're predicting a final score of Louisville 79, Stanford 66, entering tonight's matchup at Spectrum Center.

What time is Stanford vs. Louisville tonight?

Stanford vs. Louisville will begin at 7 p.m. ET tonight.

⛹️ Best college basketball betting sites

Looking to bet on college basketball tonight? Here are our best March Madness betting sites as determined by our expert team at Sportsbook Review, along with our best March Madness betting promos ahead of the NCAA Tournament.

• Caesars Promo Code: SBRBONUSDYW | Read our Caesars Review
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• bet365 Bonus Code: SBRBONUS | Read our bet365 Review
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• DraftKings Promo Code | Read our DraftKings Review

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