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Duke's Cooper Flagg drives to the basket against Wake Forest. We're backing the Blue Devils in our NC State vs. Duke prediction.
Pictured: Duke's Cooper Flagg drives to the basket against Wake Forest. Photo by Jim Dedmon via Imagn Images.

Coming off a tough win against Wake Forest this past weekend, Duke (17-2) gets a far easier opponent in NC State (9-10) when the two ACC programs take the court at Cameron Indoor Stadium in Durham, N.C., at 8:30 p.m. ET (ESPN) tonight.

Our NC State vs. Duke prediction and odds don't envision any way the March Madness odds-leading Blue Devils struggle at home against the Wolfpack.

NC State vs. Duke predictions today

College basketball picks based on the odds from our best March Madness betting sites.

  • Against the spread pick: Duke -21.5 () vs. NC State ⭐⭐⭐
  • My best pick: Cooper Flagg Over 12.5 rebounds and assists () ⭐⭐⭐

NC State vs. Duke ATS prediction

Duke to cover the spread: -21.5 ⭐⭐⭐

After its magical run to the Final Four last season, NC State is enduring one of its worst years under Kevin Keatts. The Wolfpack have lost four straight, including six of their last seven, and are 2-10 against non-mid-major opponents.

The program is just 6-13 against the spread this season, 1-6 as an underdog, and 2-6 against ACC teams. The team has covered just three times since late November.

So, I don't see how a school that's outside the top 100 in adjusted offensive and defensive efficiency, per , is going to slow Cooper Flagg and Co. 

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Flagg is the runaway favorite by the Wooden Award odds, and he's the main reason the Blue Devils are ranked as the only team in the top six in both offensive and defensive efficiency. And while this is a large spread, Jon Scheyer's squad is 7-4 ATS as a 15-plus-point favorite.

It's not just Flagg who makes Duke so dangerous, either. The Blue Devils boast the top three players in the ACC in BPR and five of the top seven, according to . NC State doesn't trot out a player ranked in the top 25.

If Duke covers, a $10 bet pays an $8.93 profit.

Best odds: -112 via DraftKings | Implied probability: 52.83%

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Best NC State vs. Duke pick

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Cooper Flagg Over 12.5 rebounds and assists ⭐⭐⭐⭐

After Flagg put the Blue Devils on his back to beat Wake on Saturday, Demon Deacons head coach Steve Forbes it best while calling the guard a generational talent. It's not just that Flagg is averaging 26.7 points per game way over his last four outings. He's doing that while impacting the game in every way.

He leads the Blue Devils in rebounds (8.0) and assists per game (4.2) while showing no signs of slowing down. The freshman phenom has topped 12.5 rebounds and assists in five of his last six games to put him at 12 games of 13-plus combined this season.

So he's going over this number in 63.1% of his outings, and NC State doesn't look like it's going to be the team to stop him with the Wolfpack sitting 245th in rebounds allowed per game (35.6). That positions Flagg well to hit this Over and turn a $10 bet into a $9.52 profit.

Best odds: -105 via FanDuel | Implied probability: 51.22%

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Live NC State vs. Duke odds

See all of this week's college basketball odds and NCAAB scores.

NC State vs. Duke opening odds

  • Spread: NC State +22.5 (-110) | Duke -22.5 (-110)
  • Over/Under: Over 134.5 (-110) | Under 134.5 (-110)
  • Moneyline: NC State +2800 | Duke -20000

NC State vs. Duke game info

  • When: Monday, Jan. 27
  • Tipoff: 8:30 p.m. ET
  • Where: Cameron Indoor Stadium (Durham, N.C.)
  • How to watch: ESPN
  • Favorite: Duke -21.5 (-112 via DraftKings)

College basketball betting odds pages

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