Iowa State vs. Arizona Prediction, Odds & Preview Today: Best Picks for Jan. 27
Last Updated: January 27, 2025 1:28 PM EST • 3 min 11 sec read.
Two of the best teams in the Big 12 square off tonight at 10:30 p.m. ET (ESPN) when Iowa State (17-2) heads to McKale Memorial Center in Tucson, Ariz. to take on Arizona (13-6) as a 2.5-point underdog.
Our Iowa State vs. Arizona prediction and odds envision the Cyclones proving why they're a March Madness odds favorite against an Arizona team that's better than its record.
Iowa State vs. Arizona predictions today
College basketball picks based on the odds from our best March Madness betting sites.
- Against the spread pick: Iowa State +2.5 () vs. Arizona ⭐⭐⭐⭐
- My best pick: Curtis Jones Over 19.5 points () ⭐⭐⭐⭐
Iowa State vs. Arizona ATS prediction
Iowa State to cover the spread: +2.5 ⭐⭐⭐⭐
After the Cyclones opened as a 1-point road favorite, this line has moved completely in Arizona's direction with the Wildcats now at -2.5. That has to be due to a combo of the Cyclones needing a second-half comeback to beat Arizona State on Saturday and Arizona blowing out its last two conference opponents.
Still, T.J. Otzelberger's team is one of the best in the country and is 8-1 against the spread in Big 12 play this season. The Cyclones are a dominant force on both ends as one of only two teams to rank in the top 10 in both adjusted offensive and defensive efficiency, according to .
This is just the third time this season Iowa State has been an underdog, and the Cyclones covered during the previous two times, one of which was against Auburn and Wooden Award odds contender Johni Broome. Meanwhile, Arizona is 10-9 ATS and 5-4 in conference play.
With Curtis Jones, Keshon Gilbert, and Tamin Lipsey leading the Cyclones, the Wildcats will struggle to slow Iowa State's offense. Arizona is outside the top 25 in D-Rate, according to .
If the Cyclones cover, a $10 bet pays a $9.52 profit.
Best odds: -105 via Caesars | Implied probability: 51.22%
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Best Iowa State vs. Arizona pick
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Curtis Jones Over 19.5 points ⭐⭐⭐⭐
Getting the Over on Jones' points at plus money via FanDuel is a terrific price given the former sixth man's recent volume. The team's leading scorer (18.6 points per game) only recently entered the starting lineup, and he's making the most of it.
Coming off a 33-point showing, Jones is averaging 24 points over his last six outings and has gone Over 19.5 in four of those games. That uptick in scoring has also coincided with him putting up more shots and playing more minutes. He's averaging 17.7 attempts in 35.5 minutes over that stretch. His season averages are 14.2 and 30.3, respectively.
Don't expect that volume to change against an Arizona defense that struggles against 3-point threats like Jones, as the Wildcats are 300th in threes allowed per game (8.3). If the former Buffalo star goes for 20-plus, a $10 bet pays a $10 profit.
Best odds: +100 via FanDuel | Implied probability: 50%
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Live Iowa State vs. Arizona odds
See all of this week's college basketball odds and NCAAB scores.
Iowa State vs. Arizona opening odds
- Spread: Iowa State -1 (-110) | Arizona +1 (-110)
- Over/Under: Over 152 (-110) | Under 152 (-110)
- Moneyline: Iowa State -115 | Arizona -105
Iowa State vs. Arizona game info
- When: Monday, Jan. 27
- Tipoff: 10:30 p.m. ET
- Where: McKale Memorial Center (Tucson, Ariz.)
- How to watch: ESPN
- Favorite: Arizona -2.5 (-106 via FanDuel)
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