Machibet777 CricketAuburn vs. Duke Prediction, Expert Picks & Odds Tonight

Duke Blue Devils guard Cooper Flagg brings the ball down court against the Maine Black Bears at Cameron Indoor Stadium as we look at our Auburn vs. Duke prediction. — Duke Blue Devils guard Cooper Flagg brings the ball down court against the Maine Black Bears at Cameron Indoor Stadium. Photo by Zachary Taft/Imagn Images.

Our Auburn vs. Duke prediction prepares you for what might be the marquee matchup of the 2024-25 college basketball season.

If it feels like I’ve said that multiple times before, it’s because this college hoops season has been rewarding us with several signature non-conference battles.

Wednesday’s showdown between No. 2 Auburn (7-0) and No. 9 Duke (5-2) might be a matchup between the country's two most talented teams.

The Blue Devils are 2.5-point home favorites ahead of a 9:15 p.m. ET tipoff (ESPN) at Cameron Indoor Stadium. But will the Tigers make a statement on the national stage?

Duke enters as the March Madness odds favorite.

Tonight's best Auburn vs. Duke picks

College basketball picks based on the odds from our best March Madness betting sites. Odds subject to change.

Against the spread pick: Duke -2.5 () vs. Auburn ⭐⭐⭐⭐
My best pick: Cooper Flagg Under 19.5 points () ⭐⭐⭐⭐

Auburn vs. Duke ATS prediction

Duke to cover the spread: -2.5 ⭐⭐⭐⭐

Best odds: -110 via BetMGM | Implied probability: 52.38%

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This could be a five-star pick if you shop for the 2-point spread at Fanatics. But I’m willing to bet on the Blue Devils recording a single-possession win at home to hand the Tigers their first loss of the season.

Auburn’s undefeated start is why bettors are getting such a good number. EvanMiya’s analytical website projects a 5.4-point line in favor of Duke, while Bart Torvik’s site forecasts a 75-70 victory for the Blue Devils.

The Tigers have been the nation's best 2-point shooting team so far this season, but I wouldn’t bet on that efficiency maintaining itself against the Blue Devils. Duke boasts the top-ranked defense in the country and is No. 1 in average height.

The Blue Devils have endured a demanding schedule, suffering losses to Kentucky and Kansas while picking up a road win over Arizona. They're prepared for this matchup, and I believe the Tigers will pick up a signature win.

Auburn vs. Duke best pick

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Cooper Flagg Under 19.5 points ⭐⭐⭐

Best odds: -104 via Caesars | Implied probability: 50.98%

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Shopping around when betting on Cooper Flagg’s scoring prop is essential. Over bettors can take advantage of FanDuel’s line (17.5), while Under bettors should grab this deal at Caesars.

I’m siding with the Under because FanDuel is one of the sharper prop betting sites among our best sportsbooks, and Auburn might defend Flagg similarly to how Kansas guarded him. The Jayhawks sent a help defender at Flagg whenever he touched the ball, limiting him to 13 points on 5-of-9 shooting.

Flagg is averaging 15.9 points per game this season while doing much of his damage as an interior scorer. Auburn’s defense ranks No. 3 overall at defending the 2-point shot, and it boasts the athletes to make this contest challenging for Flagg.

I’d bet this Under at -110 or better.

Elsewhere, our Mike Spector is eyeing Auburn standout Johni Broome for a points prop as part of his college basketball best bets for Wednesday. Broome leads the Wooden Award odds, though he's only narrowly ahead of Flagg.

Live Auburn vs. Duke odds

See all of this week's college basketball odds and NCAAB scores.

Auburn vs. Duke opening odds

Spread: Auburn +2.5 (-110) | Duke -2.5 (-110)
Over/Under: Over 146.5 (-115) | Under 146.5 (-105)
Moneyline: Auburn +125 | Duke -149

Auburn vs. Duke game info

When: Wednesday, Dec. 4
Tipoff: 9:15 p.m. ET
Where: Cameron Indoor Stadium (Durham, North Carolina)
How to watch: ESPN
Favorite: Duke -2.5 (-110 via BetMGM)

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Written By:
Shane Jackson

Shane Jackson has been writing for Sportsbook Review since 2022, though his passion for sports, writing, and betting runs much longer than that. He graduated from the University of Kansas with a journalism degree in 2017 and has been covering sports ever since, working for MLB.com, Manhattan Mercury, Lawrence Journal-World, WynnBET, Bet Chicago Sports, BetNOLA, and BetMGM. Jackson cares about creating quality sports betting content above all else. He uses a mixture of models, information, film, analysis, and a top-down approach to locate every best bet shared for SBR. He never gives out a pick that he wouldn’t be willing to spend his own money on. Jackson is focused on finding +EV bets on a daily basis for a variety of sports such as NCAAF, NCAAB, NFL, NBA, WNBA, and MLB. He usually bets on props but is willing to wager on a spread or total when there is an edge. Don’t ask him how many bets he has placed on a typical college football Saturday. Jackson doesn’t care if you follow him on social media, but his Twitter account has info on how you can follow his bets through multiple third-party platforms. He just wants you to read all the great work from the SBR team.