Syracuse vs. Pittsburgh Picks, Predictions College Football Week 10: Orange, Panthers Both Look to End Skids
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Last Updated: November 5, 2022 6:10 AM EDT • 1 min 40 sec read.
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No. 20 Syracuse visits unranked Pittsburgh in college football's Week 10. Read on for our top Syracuse-Pittsburgh picks and predictions.
The Orange and Panthers each lost back-to-back games coming into this Week 10 head-to-head battle. Syracuse likely has the more impressive losses, however, with it's defeats coming at the hands of Clemson and Notre Dame, respectively.
Meanwhile, the Panthers have lost back-to-back games by double digits. With a loss on Saturday, they would drop below .500 for the first time this season.
Here are our top picks for the college football Week 10 game between Syracuse and Pittsburgh (odds via PointsBet and DraftKings Sportsbook; pick confidence based on a 1-to-5-star scale).
Check out our college football best bets and all of our top picks for Week 10.
Syracuse vs. Pittsburgh Odds
Syracuse vs. Pittsburgh Picks
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Syracuse vs. Pittsburgh ATS Pick
Syracuse +3.5 (-110) ★★★★
The Orange may be without starting quarterback Garrett Shrader, who exited the loss against Notre Dame with an undisclosed injury. In relief, Carlos Del Rio-Wilson was decent, throwing for 222 yards, one touchdown, and one interception.
Even if Shrader doesn’t play, the Orange are simply the more talented team. They have beaten North Carolina State, Louisville, and Purdue, while the Panthers have not beaten a single FBS team with a winning record.
It’s worrying that the Orange are getting the hook at most sportsbooks, as it feels like oddsmakers are baiting bettors, but there is no way the Panthers should be favored in this game.
Syracuse vs. Pittsburgh O/U Pick
Over 48 (-110) ★★★★
Both of these teams are averaging over 30 points per game, and while the Orange are allowing less than 20, the Panthers are allowing nearly four touchdowns per contest.
These two teams can get caught in defensive struggles, but they generally do so only against defensive-minded teams.
The Orange have scored at least 21 points in all of their games this season, including last week when Del Rio-Wilson led three different scoring drives against Notre Dame. Meanwhile, the Panthers have scored fewer than 21 points just once this season.
Expect both of these teams to get at least into the mid-20s and push this easily Over.
Syracuse vs. Pittsburgh Prop Pick
Syracuse Over 21.5 (-115) ★★★
The worry seems to be whether Del Rio-Wilson will be able to move the ball for the Orange. However, those concerns are unwarranted, as last week with the Orange down 24-7, he led two third-quarter scoring drives to make it a one-possession game.
The Panthers have allowed all but one of their opponents to reach this total this season, and they have faced teams with far worse offenses than the one the Orange are putting on the field Saturday.
Where to Bet on Syracuse-Pittsburgh Picks
Syracuse-Pittsburgh picks made 11/03/2022 at 9:31 a.m. ET
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Philip Wood