Skip to main content

College Football Picks, Predictions Roundup Week 12: Expert ML, ATS, O/U, Prop Plays

Sportsbook Review

Last Updated: November 19, 2022 1:04 PM EST • 1 min 23 sec read.

Our betting experts offer their top college football picks and predictions for Week 12. Check below for all of our top against the spread, Over/Under, and prop picks on all the biggest matchups based on the NCAAF odds from our best sportsbooks.

The second-to-last full week of college football action is here! Games will be played from Tuesday through Saturday in Week 12 with conference positioning top of mind for many top teams.

Saturday's top games include Illinois at Michigan, Georgia at Kentucky, USC at UCLA, and Utah at Oregon. The race could change drastically once again based on these ranked-on-ranked matchups.

Sportsbook Review is tracking the odds to win the CFP National Championship and Heisman Trophy all throughout the 2022 college football season.

Click the links below to access our full college football picks previews for the biggest games on the Week 12 slate.

College Football Picks Week 12: Saturday

Tennessee vs. South Carolina

Spread: Tennessee -21.5 (-110 via Caesars)
Over/Under: Under 66.5 (-110 via DraftKings)
Prop: South Carolina team total Under 22.5 (-115 via DraftKings)

Ole Miss vs. Arkansas

Spread: Arkansas +2.5 (-106 via FanDuel)
Over/Under: Over 63.5 (-114 via FanDuel)
Prop: Arkansas Over 30.5 (-115 via DraftKings)

Boise State vs. Wyoming

Spread: Boise State -14 (-109 via BetRivers)
Over/Under: Under 45 (-115 via DraftKings)
Prop: Wyoming team total Under 15.5 (-120 via DraftKings)

Oklahoma State vs. Oklahoma

Spread: Oklahoma State +7 (+100 via DraftKings)
Over/Under: Over 66 (-110 via DraftKings)
Prop: Dillon Gabriel anytime touchdown (+120 via FanDuel)

USC vs. UCLA

Spread: UCLA +2.5 (-110 via Caesars)
Over/Under: Over 74.5 (-110 via FanDuel)
Prop: UCLA first-half moneyline (-105 via DraftKings)

Syracuse vs. Wake Forest

Spread: Wake Forest -9.5 (-114 via FanDuel)
Over/Under: Under 56 (-110 via DraftKings)
Prop: Wake Forest -5.5 first half spread (-110 via DraftKings)

UAB vs. LSU

Spread: UAB +14.5 (-105 via DraftKings)
Over/Under: Under 52.5 (-110 via Caesars)
Prop: LSU first half team total Over 17.5 (+100 via DraftKings)

Colorado vs. Washington

Spread: Colorado +30.5 (-105 via DraftKings)
Over/Under: Over 64 (-110 via DraftKings)
Prop: First quarter total Over 14 (-105 via DraftKings)

Utah vs. Oregon

Spread: Oregon -3 (-105 via DraftKings)
Over/Under: Over 62.5 (-110 via FanDuel)
Prop: Bo Nix Over 34.5 rushing yards (-115 via DraftKings)

Top College Football Picks for Week 12

Where to Bet on College Football

Here are our top-rated sportsbooks:

Written By:
Sportsbook Review
Free sports picks from SBR's experts. Get the latest analysis, odds and predictions on the top industry events. Home of the #SBRPros! SBR - trusted by sports bettors for over 20 years.