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Northwestern defensive back Damon Walters tries to tackle Ohio State wide receiver Jeremiah Smith. The Buckeyes' game with Indiana is the biggest matchup of our Week 13 college football predictions.
Northwestern defensive back Damon Walters tries to tackle Ohio State wide receiver Jeremiah Smith. Photo by David Banks via Imagn Images.

In the second-to-last week before conference championships, our Week 13 college football predictions look at the most important matchups this week.

  • College football championship odds favorite Ohio State takes on Indiana and its Cinderella story in a game that will impact the Big Ten Championship race
  • Led by Heisman Trophy odds favorite Travis Hunter, Colorado faces a must-win game against Kansas to keep its College Football Playoff hopes alive
  • As Army makes a push to be the Group of Five College Football Playoff odds leader, the Black Knights look to spoil Notre Dame's CFP hopes

While Week 13 lacks for  matchups, there are several marquee teams that need to win if they want to play meaningful football in late December.

College football picks & predictions Week 13

Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Don't miss the rest of our Week 13 college football picks.

College football odds for Saturday

College football odds via DraftKings and subject to change. Follow the latest college football scores for line history and matchup info.  

Army vs. Notre Dame odds

Army quarterback Bryson Daily carries the ball against North Texas. Army is part of our Week 13 college football predictions.
Army quarterback Bryson Daily carries the ball against North Texas. Photo by Danny Wild via Imagn Images.

Prediction: Jeremiyah Love Under 73.5 rushing yards (-114 via Caesars) ⭐⭐⭐⭐

Pick made by Brenden Schaeffer.

  • When: Saturday, Nov. 23 (7 p.m. ET)
  • Where: Yankee Stadium (Bronx, N.Y.)
  • How to watch: NBC, Peacock
  • Moneyline: Army (+425) | Notre Dame (-575)
  • Spread: Army +14 (-108) | Notre Dame -14 (-112)
  • Total: 44.5 (-112/-108)

Alabama vs. Oklahoma odds

Prediction: Jackson Arnold Under 178.5 passing yards (-115 via bet365⭐⭐⭐⭐  

Pick made by Phil Wood.

  • When: Saturday, Nov. 23 (7:30 p.m. ET)
  • Where: Memorial Stadium (Norman, Okla.)
  • How to watch: ABC
  • Moneyline: Alabama (-550) | Oklahoma (+410)Can
  • Spread: Alabama -14 (-108) | Oklahoma +14 (-112)
  • Total: 47.5 (-108/-112)

College football picks roundup: Week 13

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