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Notre Dame Fighting Irish quarterback Riley Leonard runs the ball against the USC Trojans, and we offer our best Indiana vs. Notre Dame player prop picks.
Notre Dame Fighting Irish quarterback Riley Leonard runs the ball against the USC Trojans. Photo by Gary A. Vasquez via Imagn Images.

An in-state battle will kick off the 12-team College Football Playoff when the 10th-seeded Indiana Hoosiers face the seventh-seeded Notre Dame Fighting Irish at 8 p.m. ET (ESPN) on Friday in Notre Dame Stadium.

  • These two teams haven’t met on the football field since 1991
  • The winner of this year’s matchup will face No. 2 Georgia on Jan. 1, 2025

The Fighting Irish are favored by more than a touchdown, but our Indiana vs. Notre Dame player prop predictions expect a competitive battle.

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Indiana vs. Notre Dame college football player prop picks: College Football Playoff

College football picks made Thursday; odds subject to change. Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

  • Riley Leonard first touchdown scorer () ⭐⭐
  • Omar Cooper Jr. Over 29.5 receiving yards () ⭐⭐⭐⭐
  • Kurtis Rourke Under 0.5 interceptions () ⭐⭐⭐

Indiana vs. Notre Dame touchdown prediction

Riley Leonard first touchdown scorer ⭐⭐

Best odds: +550 via BetMGM | Implied probability: 15.38%

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Notre Dame quarterback Riley Leonard is a threat as a runner, which is why he’s -150 to score an anytime touchdown against Indiana. But I prefer the +550 flier on him scoring the game's first touchdown instead.

Leonard has scored 14 rushing touchdowns for the Fighting Irish this season, and he scored Notre Dame’s first touchdown in six games this year. 

This line is as short as +425 at DraftKings, but a $10 bet at BetMGM offers a $55 payout.

Best Indiana vs. Notre Dame prop picks

Omar Cooper Jr. Over 29.5 receiving yards (-114) ⭐⭐⭐⭐

Best odds: -114 via FanDuel | Implied probability: 53.27%

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It’s a battle of strength on strength. Indiana ranks first in passing success rate, while Notre Dame leads the nation in passing success rate allowed.

Receiver Omar Cooper Jr. can help the Hoosiers win that battle with his big-play ability. He averaged 21.1 yards per reception this season, clearing this receiving yardage prop in nine of his 11 games. He has caught three passes in back-to-back games.

I’m betting Cooper will crack 30 yards on Friday against Notre Dame.

Kurtis Rourke Under 0.5 interceptions ⭐⭐⭐

Best odds: +104 via Caesars | Implied probability: 49.02%

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Notre Dame’s secondary is elite, but the -142 price on Indiana QB Kurtis Rourke to throw an interception is steep. After all, Rourke has thrown only four interceptions all year.

PFF has credited Rourke with eight turnover-worthy plays. His turnover-worthy play rate of 2.4% suggests he’s done an excellent job of taking care of the ball. In fact, Rourke has thrown an interception in just three different games.

I’ll take the plus-money price on Rourke maintaining that form, especially since the weather might lead to more of a run-heavy game plan.

Indiana vs. Notre Dame live odds & game info

  • When: Friday, Dec. 20
  • Kickoff: 8 p.m. ET
  • Where: Notre Dame Stadium (Notre Dame, Ind.)
  • How to watch: ESPN
  • Weather: 33 degrees, 89% chance of precipitation, NW 10 mph winds
  • Favorite: Notre Dame -7.5 (-105 via BetMGM)

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