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Colorado vs. Arizona Prediction, Picks & Odds: Week 8

Philip Wood

Last Updated: October 18, 2024 2:20 PM EDT • 3 min 15 sec read.

The Arizona Wildcats host the 4-2 Colorado Buffaloes, as both teams look to pick up Big 12 victories.

When making my best Colorado vs. Arizona prediction, it’s hard not to be a little concerned about the home team. The Wildcats have lost three of their last four games, including a 41-19 loss at the BYU Cougars last week. Additionally, quarterback Noah Fifta has thrown more interceptions than touchdowns this season.

Shedeur Sanders and the Colorado offense enter Week 8 on fire. The Buffaloes have scored at least 28 points in four consecutive games, and Sanders has thrown for at least 290 yards in each contest. We examine if they can keep it up as we make our Week 8 college football predictions.

Best Colorado vs. Arizona picks

College football picks based on the odds from our best college football betting sites. Odds subject to change.

  • Against the spread pick: Colorado +2.5 () ⭐⭐⭐⭐
  • My best bet: Shedeur Sanders Over 300.5 passing yards () ⭐⭐⭐⭐

Colorado vs. Arizona against the spread prediction: Week 8

Colorado to cover the spread: + 2.5 (-105) ⭐⭐⭐⭐⭐

Colorado vs. Arizona opening odds:

  • Colorado: +4.5 (-115 via BetMGM)
  • Arizona: -4.5 (-105 via BetMGM)

Sanders wins quarterback duel

Sanders is the fourth-leading passer in college football, while Fifita has thrown for the 21st-most yards. While neither defense is terrible against the pass, neither unit is very good. These are secondaries that can be beaten, and these offenses have the weapons to put points on the board.

However, Sanders is the much better quarterback in this matchup. He has significantly more touchdowns and yards than Fifita, and perhaps more importantly, he turns the ball over a lot less. Sanders has only thrown four interceptions this season, while Fifita has thrown nine.

While both teams have bad run defenses, neither offense is very efficient when running the ball. The Wildcats are better, with Quali Conley racking up 458 yards this season. But Conley has run for fewer than 100 yards in five of his six games, so even if he has a decent game, he won’t exploit the Buffaloes’ run defense like Kansas State did last weekend. 

This is a game that the Buffaloes can win outright, so there’s no need to wait for a key number to take them to cover the spread.

Best odds: -105 via BetMGM | Implied probability: 51.22%

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Colorado vs. Arizona best bet

Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Shedeur Sanders Over 300.5 passing yards (-115) ⭐⭐⭐⭐

The total and price combo offered by bet365 provides phenomenal value. Only two other sportsbooks are offering this prop. Caesars also has the number set at 300.5, but it's asking -127 for the over. Meanwhile, FanDuel is asking -114 for over 313.5, which implies almost the same probability as bet365 for 13 more yards.

Sanders has thrown for at least 300 yards in four of his six games this season. He’s only thrown for fewer than 290 yards once, and that performance was back in Week 2. Last season, Sanders only threw for 262 yards against the Wildcats. However, this year’s Wildcats pass defense is worse than last year’s.

Based on recent defensive performances, this should be a shootout. Shootouts are when Sanders is at his best

Best odds: -115 via bet365 | Implied probability: 53.49%

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Colorado vs. Arizona odds

See all of this week's college football odds and NCAAF scores.

Colorado vs. Arizona game info

  • When: Saturday, Oct. 19
  • Kickoff: 4 p.m. ET
  • Where: Arizona Stadium (Tucson, Ariz.)
  • How to watch: FOX
  • Weather: 72 degrees, 0% chance of precipitation, wind 6 mph W
  • Favorite: Arizona -2.5 (-115 via BetMGM)

College football betting odds pages

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Written By:
Philip Wood
Phil has covered sports betting since 2016, and he has been with SportsBook Review since 2022. He previously hosted the College Football Pick 'Em podcast for CanesInsight.com. He is always looking for value, especially on lines that just seem too good to be true. His belief is that if a line doesn't make sense just assume oddsmakers know something you don't. He also loves in-season futures. There is so much value to be had as the public overreacts weekly. Bettors tend to forget just how long NFL and college football seasons are. After all, the Green Bay Packers were 2-5 in 2023 and they made it to the Divisional Round. When deciding where to bet, it comes down to value over everything. +100 is always better than -110. An alumnus of The U, Phil always holds out hope that the next head coach will be the one who turns the football program around. He is also a diehard Detroit Lions fan and is willing to forgive Dan Campbell for forgetting that a kicker can be useful.